Copenhagen, having secured a remarkable victory against Manchester United en route to their second-place finish in Group A, stands as the least highly ranked team remaining in the UEFA Champions League.
In another matchup, Barcelona is set to take on Napoli, a fixture noteworthy for both teams being former clubs of the late Argentine legend Diego Maradona.
Borussia Dortmund and PSV Eindhoven have been paired together in the draw for the next round.
In their first appearance in the round of 16 since the 2016-17 season, Arsenal will face two-time winners FC Porto, while Bayern Munich is set to take on Lazio.
Paris Saint-Germain, who secured the second spot in Group F after Borussia Dortmund, will play against the Spanish side Real Sociedad.
The round of 16 commences with group winners hosting the first-leg matches, scheduled for February 13, 14, 20, and 21. The return legs are slated for March 5, 6, 12, and 13.
This marks the final season of the traditional format, transitioning to a 36-team competition with a knockout bracket primarily based on final positions.
The grand finale is scheduled for June 1 at Wembley Stadium in London, England.Top of Form
Confirmed UCL round of 16 ties
FC Porto vs. Arsenal
SSC Napoli vs. Barcelona
Paris Saint-Germain vs. Real Sociedad
Inter vs. Atletico Madrid
PSV Eindhoven vs. Borussia Dortmund
SS Lazio vs. FC Bayern Munchen
FC Copenhagen vs. Manchester City
RB Leipzig vs. Real Madrid
Confirmed UEL knockout round play-off ties
Feyenoord vs. Roma
Milan vs. Rennes
Lens vs. Freiburg
Young Boys vs. Sporting CP
Benfica vs. Toulouse
Braga vs. Qarabag
Galatasaray vs. Sparta Praha
Shakhtar Donetsk vs. Marseille
Confirmed UECL knockout round play-off ties
Sturm Graz vs. Slovan Bratislava
Servette vs. Ludogorets
Union SG vs. Eintracht Frankfurt
Real Betis vs. Dinamo Zagreb
Olympiacos vs. Ferencvaros
Ajax vs. Bodo/Glimt
Molde vs. Legia Warsaw
Maccabi Haifa vs. Gent